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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BBMD3 (berbamine derivative) Cell viability- determination of IC50 value MTS Assay N/A N/A A2058 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 2.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 3.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 4.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Cell viability ELISA 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens p-STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens STAT3
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens p-STAT3(Tyr705)
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 1.00 µM A2058 Homo sapiens p-STAT3(Tyr705)